Correlation between prostate MRI results and histopathological examination of prostate biopsy cores in patients followed in the CNHU-HKM University Urology-Andrology Clinic

Abstract

Introduction: Multiparametric MRI currently plays an important role in the detection and localisation of prostate tumour foci.

Materials and Methods: This was a descriptive and analytical study. The study was conducted from June 1, 2021, to June 31, 2023. All patients with a lesion classified as at least PIRADS 3 on prostate MRI who underwent a prostate biopsy were included.

Results: A total of 213 patients were included, with a mean age of 66.18 years. Elevated PSA levels (78.81%, n = 170) and/or abnormalities on digital rectal examination (45.54%, n = 96) were the indications for MRI. The mean prostate volume on MRI was 67.77 cm³. Suspicious lesions on MRI were present in 155 (72.76%). Prostate cancer was identified by prostate biopsy in 70.86% (n = 107) of cases, of which 62.60% (n = 72) were clinically significant. Locoregional involvement was present in 68 patients (31.92%). The presence of prostate cancer and its clinical significance were also discussed. The presence of prostate cancer, its clinical significance, and its loco-regional extension were associated with PIRADS lesions on prostate MRI, with p-values of p = 0.0002, p = 0.02, and p = 0.004 respectively.

Conclusion: Multiparametric prostate MRI is therefore a good diagnostic tool for assessing the locoregional extent of prostate tumours.